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Pubmed- Young-onset stroke complicating ulcerative colitis

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Posted 08 January 2022 - 09:31 PM


Pract Neurol. 2022 Jan 7:practneurol-2021-003106. doi: 10.1136/practneurol-2021-003106. Online ahead of print.


A 16-year-old girl developed a proximal occlusion of the right middle cerebral artery during a flare-up of acute ulcerative colitis. Although mechanical thrombectomy led to successful middle cerebral artery recanalisation, she required an immediate second thrombectomy due to reocclusion of the same arterial segment. She developed a second ischaemic event 7 days later despite intravenous heparin infusion, later switched to low-molecular-weight heparin, and a third event after 3 days despite the addition of aspirin. We discuss stroke risks in people with inflammatory bowel disease and the uncertainties around anticoagulation and antiplatelet regimens in such cases.

PMID:34996841 | DOI:10.1136/practneurol-2021-003106

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